The associations between vaccination status, type, and time since vaccination with lineage identity during the emergence of new SARS-CoV-2 variants CDCgov SUNY vaccine vaccination covid coronavirus COVID19
By Pooja Toshniwal PahariaSep 7 2022Reviewed by Danielle Ellis, B.Sc. In a recent study published in Emerging Infectious Diseases, researchers assessed the association between severe acute respiratory syndrome coronavirus 2 strains and patient age, coronavirus disease 2019 vaccination status, vaccine type, and days elapsed since the most recent vaccination among New York residents.
A viral genomic sequence dataset linked with demographic and vaccination data obtained from records of the communicable disease electronic surveillance system and New York state immunization information system, respectively, was used for the analysis. The case patient group comprised individuals infected with the emerging SARS-CoV-2 strain, whereas the control group comprised individuals infected with any other SARS-CoV-2 strain.
Delta emergence was analyzed between 19 March 2021 and 15 August 2021, with 603 case patients and 1,816 controls, respectively. The control group comprised individuals infected with B.1.1.7 and Q.4 Alpha , B.1.526 Iota , P.1.X Gamma , and B.1.351.X Beta . Logistic regression modeling was used with models selected based on the Akaike information criterion scores, and odds ratios were calculated.
The sample population for Pfizer, Moderna, and Janssen vaccinations comprised 177, 109, and 22, respectively. Omicron infections showed the greatest associations with the status of prime vaccinations and booster vaccinations, with OR values of 3.1 and 6.7, respectively. On removing patient age as a criterion for matching , lower age was predictive of Omicron infections and OR values for the status of prime vaccination and third vaccination were greater compared to those obtained previously.
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