Researchers and physicians from Sunnybrook and sickkids led the world’s first clinical trial of a groundbreaking new treatment for pediatric brain cancer. Here’s what happened inside their OR:
In early January, a team of researchers and physicians from Toronto’s Sunnybrook and SickKids hospitals completed the first step in a world-first clinical trial of a new treatment for pediatric brain cancer. They used MRI-guided ultrasound to temporarily open the blood-brain barrier
One cannot intervene in the brain stem surgically in any capacity, let alone resect a tumour, without risking any or all of these functions. At the same time, the work I led at Sunnybrook amassed an experience of BBB-opening in adult patients across multiple indications, including primary and secondary brain tumours, Alzheimer’s and Parkinson’s disease. This gave us compelling data that opening the BBB in human patients can be done safely.Walk me through January 4, the day you treated your first patient.The patient is a five-year-old girl: the youngest allowed for our trial.
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