New clues into how the circadianclock helps the brain recover after injury ChildrensHealth SfNJournals
, the findings open new avenues of investigation for future TBI therapies. These injuries are currently managed only with supportive care and rehabilitation, rather than targeted drug treatment options. The findings also underscore the importance of addressing circadian disturbances to help injured brains heal.
cell—known as NG2-glia, or oligodendrocyte precursor cells—also follow a circadian rhythm. This cell type is one of the few that continually self-renews throughout adulthood and is notably proliferative in the first week after brain injuries.circadian clock Sometimes called"the silent epidemic," TBI afflicts an estimated 69 million people worldwide each year, with injuries ranging from mild concussions tothat cause mortality or lifelong disability. In the United States alone, approximately 2.8 million people sustain TBI annually, including 630,000 children. TBI is the leading cause of death in people under age 45, and those who survive are often left with persistent physical, cognitive and psychological disabilities.
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