Researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging.
By Pooja Toshniwal PahariaAug 28 2023Reviewed by Lily Ramsey, LLM In a recent review published by Molecular Psychiatry, researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging and positron emission tomography imaging in dementia diagnosis.
About the review In the present review, researchers presented the role of neuroimaging in dementia diagnosis. Volumetric MRI alterations, on the other hand, are insensitive in early prodromal dementia phases and generally correspond with established neurodegenerative processes. Serial MRI has been utilized to enhance dementia differential diagnosis and is frequently employed as a secondary outcome measure in treatment studies.
F-FLUORODEOXYGLUCOSE PET imaging in identifying neurodegenerative diseases FDG-PET, which measures the local brain metabolic rate of glucose consumption, is commonly used to diagnose Alzheimer's disease and other kinds of dementia. It has a high specificity in identifying approximately half of the individuals with behavioral variant FTD who are undetectable by MRI, allowing the exclusion of psychiatric and other neurodegenerative illnesses.
However, it has a few limitations, including the fact that it is not correlated with symptomatic onset or disease severity, that it cannot predict dementia onset, and that more research is required for older individuals due to the prevalence of amyloid pathology among a large fraction of the older and cognitively unimpaired population.
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