Nature research paper: Y chromosome loss in cancer drives growth by evasion of adaptive immunity
Z.L. reports personal consultation fees from Alphamab, HanchorBio, Henlius, Heat Biologic and Ikonisys outside the submitted work. All other authors declare no competing interests.thanks Mitchell Machiela, Soichi Sano and the other, anonymous, reviewer for their contribution to the peer review of this work.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Extended Data Fig.
1 LOY is associated with a worse clinical outcome for patients with MIBC and NMIBC., Y chromosome genes expressed in normal bladder urothelium that were used to create a Y chromosome gene expression signature.-values based on stratification by Y chromosome gene expression on TCGA MIBC patient overall survival .
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