With winter fast approaching, to escape the cooler temperatures and as the days get darker,...
With winter fast approaching, to escape the cooler temperatures and as the days get darker, we tend to spend more time socialising inside. The problem that brings is viruses such as Covid and flu spread much more easily in confined, less well ventilated spaces. The good thing is we have the tools to keep ourselves protected against severe disease this season.
This winter Covid and flu could be circulating at high levels – with flu in particular expected to be higher than recent years – which would put increasing pressure on hospitals and other healthcare services. For these reasons, everyone aged 50 and over, along with people in specific risk groups, are being offered both a flu and Covid booster jab to top up their immunity.
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Lancashire braced for toughest winter since before CovidA depleted and now 'fatigued' social care workforce has seen pressures stay the same since Covid as more residents ask for help
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Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study - Critical CareBackground The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 and non-COVID-19 critically ill patients. Methods We used data from the Eurobact II study, a prospective observational multicontinental cohort study on HABSI treated in ICU. For the current analysis, we selected centers that included both COVID-19 and non-COVID-19 critically ill patients. We performed descriptive statistics between COVID-19 and non-COVID-19 in terms of patients’ characteristics, source of infection and microorganism distribution. We studied the association between COVID-19 status and mortality using multivariable fragility Cox models. Results A total of 53 centers from 19 countries over the 5 continents were eligible. Overall, 829 patients (median age 65 years [IQR 55; 74]; male, n = 538 [64.9%]) were treated for a HABSI. Included patients comprised 252 (30.4%) COVID-19 and 577 (69.6%) non-COVID-19 patients. The time interval between hospital admission and HABSI was similar between both groups. Respiratory sources (40.1 vs. 26.0%, p | 0.0001) and primary HABSI (25.4% vs. 17.2%, p = 0.006) were more frequent in COVID-19 patients. COVID-19 patients had more often enterococcal (20.5% vs. 9%) and Acinetobacter spp. (18.8% vs. 13.6%) HABSIs. Bacteremic COVID-19 patients had an increased mortality hazard ratio (HR) versus non-COVID-19 patients (HR 1.91, 95% CI 1.49–2.45). Conclusions We showed that the epidemiology of HABSI differed between COVID-19 and non-COVID-19 patients. Enterococcal HABSI predominated in COVID-19 patients. COVID-19 patients with HABSI had elevated risk of mortality. Trial registration ClinicalTrials.org number NCT03937245 . Registered 3 May 2019.
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Michelin-starred Star Inn The Harbour to close with Andrew Pern blaming Scarborough Council's lack of supportWhitby’s Michelin-listed Star Inn the Harbour is to close on November 12 with restaurateur Andrew Pern blaming Scarborough Council for its lack of support through Covid.
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The impact of genetic and lifestyle factors on the risk of major cardiovascular and thromboembolic events post-COVID-19 diagnosisThe impact of genetic and lifestyle factors on the risk of major cardiovascular and thromboembolic events post-COVID-19 diagnosis medrxivpreprint UniofOxford LSHTM Cambridge_Uni ErasmusMC
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