The obesity\u002Ddrug gold rush, Reuters reports, is expected to reach US$50 billion annually by 2030
“Mounjaro has not been submitted for Canadian regulatory approval for weight management, and although it may be submitted for this indication in the future we are not permitted to speak about the product, off-label,” the company said.
But Mounjaro, chemical name tirzepatide, targets a second hormone, GIP, that also works to decrease food intake.published last year, people on Mounjaro lost, on average, 19.5 to 21 per cent of their body weight over 72 weeks, depending on the dosage, “an unusually substantial degree of weight reduction” for a weight-loss drug, the authors wrote, and one that’s approaching the numbers seen with bariatric surgery.
But while they’re not medical miracles, the new drugs do seem “vastly better” than what came before them, wrote pharmacist and obesity health-care professional Ted Kyle on his blog, ConscienHealth. When food enters the stomach, ghrelin, the hunger hormone, gets suppressed, and GLP-1 and GIP are released from the intestine. Those gut-secreted hormones signal to the brain “we’re full.”
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