Widely available supplement may explain brain boost from exercise

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Widely available supplement may explain brain boost from exercise
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The chemical element selenium may be the key to how exercise boosts the brain’s ability to create new neurons, according to new studies in mice.

“I’ve been working on neurogenesis for almost 20 years … and we’ve never seen anything like that before,” Walker says.

“It’s the first time a substance that is usually in the diet has been found to have such a relevant and clear effect in neurogenesis,” says Juan Encinas, a neurobiologist at the Achucarro Basque Center for Neuroscience. But he saysTo find out whether selenium can help the aging brain, Walker’s team added selenomethionine to the drinking water of 18-month-old mice . After nearly 1 month, the number of new neurons in the rodents’ hippocampi had doubled.

Finally, the researchers investigated whether selenium could help reverse the cognitive deficits that result from brain injury. They injected a molecule into the mice’s hippocampus to cause a strokelike lesion that destroys neurons and hurts memory. The lesioned but treated mice performed just as well as normal mice on a suite of memory tasks.

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