The evidence calls for treatment guidelines to be changed. According to a world-first trial led by the University of Sydney, opioids are no more effective than a placebo for treating acute back and neck pain and could even be harmful. The research team argues that this evidence calls for an upda
Therecruited close to 350 participants from 157 primary care and emergency department sites. Participants with acute-meaning sudden and generally short-term back or neck pain were randomly allocated to a six-week course of a commonly prescribed opioid or a placebo.
“Not even when other drug treatments are not able to be prescribed or have not been effective for a patient.”into opioid use for chronic low back pain which found a small treatment benefit, but increased risk of harm.Reducing the overuse of opioids is a global health priority. Medical authorities around the world have cautioned that due to the significant risk of harm to individuals and society, opioids should only be used where there is evidence that the benefits outweigh the harms.
“The possible harmful effects of opioids are well known. They range from minor harms such as constipation and drowsiness to major harms such as dependence, addiction, overdose, and even unintentional death,” said Professor McLachlan.
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