What is the efficacy of the BCG vaccine against SARS-CoV-2 infection? Brown_SPH Vaccine BCGVaccine SARSCoV2 COVID19
By Bhavana KunkalikarSep 22 2022Reviewed by Aimee Molineux In a recent study published in the PLOS ONE journal, researchers assessed the ecological association suggesting the efficacy of bacillus Calmette-Guerin vaccination against coronavirus disease 2019 .
The team repeated the analysis performed by Miller et al. using the same statistical techniques to judge the reliability of their results for each month in 2020 after their analysis in March 2020. Those authors used COVID-19 data from Google News to analyze the association between BCG vaccination and COVID-19 morbidity and mortality from 1 January 2020 to 21 March 2020. The team used information on COVID-19 infection and mortality from the COVID-19 Data Repository at Johns Hopkins University.
Results Related StoriesMiller et al. investigated 55 middle/high- and high-income nations that had universal BCG vaccination policies in place, as well as five that had never had this policy. Wilcoxon Rank Sum Tests revealed that, as of March 2020, COVID-19 incidence, mortality, and mortality-to-incidence ratios were statistically significantly lower in countries with universal immunization programs than in those without such BCG regulations.
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