Venetoclax Plus Gilteritinib for FLT3-Mutated Relapsed/Refractory Acute Myeloid Leukemia | Journal of Clinical Oncology

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Venetoclax Plus Gilteritinib for FLT3-Mutated Relapsed/Refractory Acute Myeloid Leukemia | Journal of Clinical Oncology
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Improving drug therapy for relapsed leukemia northwesternu nejm

); response occurred rapidly after achieving at least BM remission , if needed, for count recovery after achieving BM remission; and using azole antifungals to reduce fungal infections with appropriate venetoclax dose reductions.

Although survival reported here is similar to that reported in ADMIRAL, VenGilt response rates and OS are encouraging, as our study included all salvage patients , whereas ADMIRAL included only first relapse/primary refractorypatients. Furthermore, this study included a substantially higher proportion of patients who received ≥ 1 prior FLT3 TKI compared with ADMIRAL (59%

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