Scientists are racing to find novel alternatives to traditional antibiotics, a hunt that is uncovering unusual ways to counter infection, in unusual places.
NEW HAVEN, Conn. — Bacteria lodged deep in Ella Balasa’s lungs were impervious to most antibiotics. At 26, gasping for breath, she sought out a dramatic experiment — deliberately inhaling a virus culled from sewage to attack her superbug.“I’m really running out of options,” said Balasa, who travelled from her Richmond, Virginia, home to Yale University for the last-resort treatment. “I know it might not have an effect.
Gallium doesn’t nourish and knocks other systems out of whack, Goss said.For two small studies, the researchers recruited cystic fibrosis patients who had antibiotic-resistant pseudomonas in their lungs but weren’t openly sick. The patients received a five-day infusion of a gallium-based drug. Over the next few weeks, their lung function improved, enough that next-step studies are being planned.
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