UK girl’s hearing restored after groundbreaking gene therapy

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UK girl’s hearing restored after groundbreaking gene therapy
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Opal, an 18-month-old British girl born deaf, received groundbreaking gene therapy, restoring her hearing to near-normal levels.

UK toddler Opal underwent pioneering gene therapy at Cambridge's Addenbrooke's Hospital, marking a new era in deafness treatment.An 18-month old British girl who was born completely deaf is believed to be the youngest person to have their hearing restored after undergoing groundbreaking new gene therapy.

Opal was treated at Addenbrooke’s Hospital in Cambridge, part of Cambridge University Hospitals NHS Foundation Trust, in eastern England. Auditory neuropathy can be caused by a fault in the OTOF gene, which is responsible for making a protein called otoferlin. This enables cells in the ear to communicate with the hearing nerve.

Medics in Philadelphia have also reported a good outcome with a type of gene therapy on an 11-year-old boy.

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