Norman “Ned” Sharpless, director of the $6.9 billion National Cancer Institute since late 2017, has announced that he will step down in late April after nearly 5 years on the job.
he’s returning to his family in North Carolina, where his wife is an endocrinologist and his aging mother lives. He doesn’t yet have another position, but says he expects to return to academia.
Varmus said it was “wonderful to be succeeded [at NCI] by somebody as good as Ned.” He credits Sharpless with “paying attention to all the right things.” Sharpless “did a great job during a difficult time,” says Ellen Sigal, founder and chair of Friends of Cancer, an advocacy group. “Ned’s vision and enthusiasm will be greatly missed,” adds David Tuveson, director of the Cold Spring Harbor Laboratory Cancer Center and president of the American Association for Cancer Research. , the program he created in 2016 as vice president, with a new goal of halving the cancer death rate within 25 years. Biden’s 2023 budget proposal gives NCI no new funding for the moonshot, however. Instead, NCI would get a 3% cut, and nearly all of a proposed $4.
Now, Biden will have an opportunity to name the next NCI director, who will face the task of shaping the institute’s role in these initiatives. The White House faces no deadline in making its pick, however, and still needs to fill the role of NIH director, vacant since Francis Collins stepped down in December 2021. In the meantime, NCI Principal Deputy Director Douglas Lowy will serve as the institute’s acting director.
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