Hanser Alberto and Seby Zavala homered for Chicago.
The White Sox, who came in hitting .180 with runners in scoring position over the past 13 games, went 1 for 8 in those situations on Saturday.
Reds third baseman Nick Senzel stranded a pair of runners in the first when he retired Andrew Benintendi with a diving stop. The White Sox left the bases loaded in the third. Lodolo allowed three runs and six hits in 3 2/3 innings. He hit three batters, struck out three and walked one. Friedl's homer was the sixth allowed by Clevinger in the pitcher's last four starts. Clevinger has allowed 15 earned runs over his last four starts.
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