Blood-based cancer screening company Thrive Earlier Detection Corp. released data from a phase one study that showed its diagnostic test was able to detect some early-stage cancers in patients without any cancer symptoms
Blood-based cancer screening company Thrive Earlier Detection Corp. released data from a phase one study that showed its diagnostic test was able to detect some early stage cancers in patients without any cancer symptoms.Science
and done in collaboration with the Johns Hopkins Kimmel Cancer Center, found 26 new cancers in more than 9,900 women who had no history of cancer nor any symptoms of disease. The blood test was able to signal the potential presence of cancer, but not where in the body cancer was located; that was diagnosed using a PET-CT scan.
A blood test followed by a scan had a 99.6% specificity , but the blood test on its own has a sensitivity of 31%, meaning there may have been a number of cancer cases that were missed by the test. David Daly, CEO of Thrive, says the liquid biopsy test should be used alongside regular cancer screenings like mammograms and colonoscopies, and should not be used to replace them.Nickolas Papadopoulos, an oncologist at Johns Hopkins and a senior author of the study, said he isn’t bothered by potential false negatives because the cancers that were caught are normally diseases for which no screening tests are available, such as uterine and kidney cancer.
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