Nanotechnology offers promising advancements in diagnosing and treating endometriosis, improving accuracy, minimizing invasiveness, and enhancing therapeutic effectiveness.
By Nidhi DhullJun 19 2024Reviewed by Lexie Corner Endometriosis is an incurable gynecological disorder characterized by abnormal growth of endometrial-like tissue outside the uterine cavity, causing pelvic pain and fertility issues in millions. Affecting about 10 % of reproductive-age women, endometriosis leads to impaired quality of life due to recurrence after existing treatments.
The potential of nanoparticles to dissolve insoluble drugs, prevent degradation of therapeutic agents, increase drug circulation time, target drug delivery, and reduce systemic toxicity is well established today; they are often referred to as modern “magic bullets.” This targeted method improves imaging during endometriosis diagnosis and offers a deeper understanding of the disease's origin and advancement.1
Specifically, nanoparticles can ensure targeted delivery of antioxidants or antiangiogenic compounds to prevent endometriosis progression.2 Gene therapy involves altering genetic material for disease prevention and treatment by adding, correcting, or removing specific genes. This can be realized by delivering nucleic acids containing specific genes in the body.1
However, mouse and rat models are inaccurate as endometriosis does not grow naturally in these animals. A primate reproductive model is more suitable for endometriosis treatment trials due to its closer similarities to the human reproductive system.2
Endometriosis Treatment Nanomedicine Advanced Nanotechnology
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