'Superager' Genes Can Shave a Decade Off Heart Age, Scientists Say

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'Superager' Genes Can Shave a Decade Off Heart Age, Scientists Say
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'Our findings confirm the healthy mutant gene can reverse the decline of heart performance in older people.'

known as BPIFB4 in 2018, the researchers conducted experiments on human cells in test tubes and later on mice to see if the genes were still able to turn back the biological clock when introduced in a lab instead of being inherited.

Incredibly, they found that its introduction to damaged cells can both halt and even reverse heart aging. "The cells of the elderly patients, in particular those that support the construction of new blood vessels, called 'pericytes', were found to be less performing and more aged," said Monica Cattaneo, a researcher at the MultiMedica Group in Italy and co-author, in a"By adding the longevity gene/protein to the test tube, we observed a process of cardiac rejuvenation: the cardiac cells of elderly heart failure patients have resumed functioning properly, proving to be more...

The researchers also found that those same cells seemed to have reduced expression of BPIFB4 as well.

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