Study reports outbreak of C. vulturna in a hospital in China CDCgov EIDjournal infection disease outbreak antifungal fungal
By Pooja Toshniwal PahariaJun 15 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in Emerging Infectious Diseases, researchers reported an increase in Candida vulturna infections among residents of China between 2019 and 2022.
About the study In the present study, researchers assessed deidentified data from individuals hospitalized in the Shanxi Province of China due to Candida vulturna infections. Further, phenotypic analysis and antifungal drug susceptibility testing were performed using one representative strain from each patient to determine the antifungal of choice based on the minimum inhibitor concentration values, expressed as mg per liter, and the cut-offs used for Candida albicans.
All the fungal strains detected clustered in the same clade and showed phylogenetic similarities. Since PICCs were used to deliver drugs to all the study participants and Candida vulturna was detected in the peripherally inserted central catheter tips among seven patients, PICC line usage may be considered a factor that increases the risk of Candida vulturna infections.
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