A new study has shown that subclinical hypothyroidism diagnosed before 21 weeks of pregnancy is associated with more than fourfold higher rates of overt hypothyroidism or thyroid replacement therapy within 5 years of delivery.
University of Utah HealthAug 2 2024 The study is published in the peer-reviewed journal Thyroid ®, the official journal of the American Thyroid Association® .
Michael Varner, MD, professor of obstetrics and gynecology in the Spencer Fox Eccles School of Medicine at University of Utah Health, and his coauthors reported that progression to overt hypothyroidism was more common in individuals with thyroid-stimulating hormone levels that were more than twice the normal level.
The investigators found that diagnosis of hypothyroxinemia, a deficiency in the thyroid hormone thyroxine, before 21 weeks of pregnancy was not associated with the development of overt hypothyroidism after delivery.
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