Study explores the association between prenatal air pollution exposure and changes in neonatal brain structure env_int_journal KingsCollegeLon imperialcollege prenatal airpollution childhealth childrenshealth infanthealth health infant neonatal
By Bhavana KunkalikarApr 12 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Environment International Journal, researchers explored the impact of air pollution exposure during pregnancy on the neonatal brain.
Maternal exposure during pregnancy can negatively affect brain development, potentially leading to cognitive dysfunction. Animal studies have produced inconsistent findings regarding the link between air pollution exposure during the prenatal stages and brain development in early life. The study included neonatal scans of subjects born between 2015 and 2020. The study cohort included 782 infants in the dHCP project, with 469 infants in the final sample. An online tool was used to calculate the Index of Multiple Deprivation for all infants based on their postcode at birth.
Results The study included 469 infants born with a median gestational age of 40.14 weeks and underwent imaging at 41.29 weeks postmenstrual age. Additionally, these factors were associated with a larger brainstem along with extracerebral cerebrospinal fluid in the first mode. No significant association was found between exposure to PM10 and brain volume measures.
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