Sinus Inflammation Could be the Reason Behind Persistent Brain Fog

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Sinus Inflammation Could be the Reason Behind Persistent Brain Fog
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Chronic sinusitis could mess with your thinking. Researchers are trying to figure out the link between sinus inflammation and brain fog.

of the U.S. population — a stuffy nose and postnasal drip may be the least of your worries. Research has uncovered a link between chronic sinusitis and cognitive deficits — or, as most people who have this problem call it, “brain fog.”, a surgeon and an assistant professor in the Department of Otolaryngology–Head and Neck Surgery at the University of Washington School of Medicine.

So, he and colleagues gave 24 volunteers who suffer from chronic sinusitis a battery of cognitive tests, including the Montreal Cognitive Assessment and the Neuro-OOL Cognitive Function tests. They also tested the participants with software that tracked their eye movements while they performed onscreen tasks, a common way of assessing cognitive ability. Participants also filled out the delightfully named SNOT-22 quality of life questionnaire.

The study found decreased connectivity in the frontoparietal cortex, what Jafari describes as the “central hub” or “gatekeeper” of a lot of neural signaling. “Interestingly,” he says, “that network sits really close to the interface between the brain and the sinus.” Still, Jafari suspects that the problem is a result of a massive inflammatory reaction in the body that crosses the blood-brain barrier.

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