An antibacterial compound delivered inside microscopic envelopes could soon bring relief to hundreds of millions with the inflammatory skin condition acne vulgaris.
While there are ways to curtail the bacteria's growth, such as through antibiotics or hormones that reduce the skin oils that feed the microbes, many come with side effects or are becoming.
In fact, the team found that their special nanoparticle delivery system improved solubility by more than 100 times, compared to a simple water mix. This was due in part to the use of, a compound that improved the solubility of the nano-micelles and the stability of the drug delivery.
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