Scientists discover key mechanism in Ebola virus replication, opening door to new treatments.
Ebola, the notorious pathogen responsible for devastating outbreaks and high mortality rates in sub-Saharan Africa, has long posed a significant threat to
Model of VP35 interacting with Ubiquitin. The complex of VP35 and Ubiquitin modeled using a combination of protein docking and molecular dynamics simulations.The researchers focused on the interaction between ubiquitin, a protein found in human cells, and the Ebola virus VP35 protein. This interaction is key to the virus’s ability to replicate and evade the immune system.
The study delved into the complex molecular processes of viral replication with the help of advanced techniques in molecular biology, cell biology, biophysics, and computational modeling. These tools enabled the researchers to tease apart the interactions between Ebola virus proteins and human proteins – interactions essential for the virus to thrive.
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