Scientists knew phenylephrine was useless—but you’ve been using it for decades

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Scientists knew phenylephrine was useless—but you’ve been using it for decades
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More than 200 over-the-counter decongestants contain a key ingredient that was just revealed to be ineffective—and cold and flu season is just around the corner. Now what?

Finally, on September 11 and 12, 2023, an advisory committee to the FDA reviewed data and clinical trials that were presented in an 89-page report and concluded that orally administered phenylephrine doesn’t relieve nasal congestion.

The following year, access to pseudoephedrine was restricted and the drug was placed behind the counter at pharmacies, requiring customers to request it, show ID, and have their purchasing habits of the drug tracked. This was to prevent people from buying large quantities and using it to manufacture methamphetamine, a highly addictive stimulant .

Experts say that while some consumers are surprised by the announcement that it isn’t effective, others aren’t. Others have a better-late-than-never mindset. “The upshot is: We can reduce patients’ financial burden from buying products that are not effective,” says Mark Sullivan, chief pharmacy officer with Vanderbilt Health in Nashville. “The FDA is looking through the data which instills confidence for what they’re doing for public” well-being.With cold and flu season approaching, many people are wondering which OTC medicines to stock up on and which ones to ditch.

Still, many doctors say that OTC nasal steroid sprays are the most effective approach for reducing nasal inflammation and congestion. But “they don’t work immediately—you have to use them every day,” Talmadge says. Nasal antihistamine sprays also can be helpful for nasal congestion that’s due to allergies or colds, Parikh says.,” Dykewicz adds. But “if oral decongestants aren’t getting the job done, nasal sprays can do much better.

in Cleveland. Plus, oral pseudoephedrine can cause problematic side effects such as increased heart rate or palpitations, spikes in blood pressure, or difficulty sleeping.

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