One of the key advantages of this treatment is its topical application, which can expedite approval processes due to lower risks of adverse effects.
Under the leadership of Professor Maria Elena de Lima, researchers from the Federal University of Minas Gerais embarked on a journey to understand the pharmacological mechanisms behind priapism caused by the spider's venom. Their ultimate goal was to develop a safe and effectiveThe result of their efforts is a synthetic molecule named BZ371A. This molecule has garnered 22 international and nine applied patents, underscoring its potential as a groundbreaking solution.
Further research, including the crucial contribution of Carolina Nunes da Silva, led to the identification of the synthetic peptide PnPP-19. This peptide, derived from the spider's toxin, proved to be a potential model for erectile dysfunction treatment.The drug candidate BZ371A recently received approval for phase 1 clinical trials by the Brazilian Health Regulatory Agency . Early trials have already shown that the compound is non-toxic to humans, a crucial milestone in drug development.
Paulo Lacativa, the executive director of Biozeus, believes this project could mark a historic moment for Brazilian research and innovation. He envisions it as an opportunity for Brazil to lead the way in developing a medication with global implications, showcasing the country's prowess in drug development.
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