The team developed antimicrobial peptides that can cluster to trap and kill antibiotic-resistant bacteria. Read more at straitstimes.com.
SINGAPORE – With bacteria becoming increasingly resistant to even the strongest antibiotics, scientists around the world have been urgently trying to develop new drugs to prevent this “silent pandemic” from worsening.– more than the current number of deaths caused by cancer.
The nano-nets developed by the team mimic a natural body response to pathogens at various sites such as the small intestine, urinary tract and blood vessels. Though the nano-nets have not been tested in humans, the researchers theorise that the trapping of bacteria in the body by the nets would make the germs more vulnerable to antimicrobial compounds secreted by the immune system – essentially augmenting the human body’s innate ability to combat bacterial infections.
“In addition, most of the synthetic peptide nano-nets that have been developed so far can only trap bacteria, whereas the modifications we made allowed our nano-nets to both trap and kill them.”Prof Ee highlighted that the nano-nets had some advantages over antibiotics in their ability to kill bacteria.
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