Researchers discuss strategic actions to stimulate research on fungal diseases in the context of the WHO fungal pathogens priority list PLOSNTDs EinsteinMed fungi disease fungus pathogen fungal
By Bhavana KunkalikarMar 27 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in the PLOS Neglected Tropical Diseases journal, researchers in the United States and Brazil explored priority fungal pathogens recognized by the World Health Organization .
Knowledge creation in medical mycology The publishing rates in antifungal research are significantly lower than, for example, those in antibacterial research. The team conducted PubMed searches utilizing the WHO terms provided in the list. This research indicates that the development of information in fungal infections is highly variable and presumably uncorrelated with mortality or disability-adjusted life years .
In conclusion, the rate of knowledge production has remained steady over the past decade for nearly 70% of the fungal pathogens studied, regardless of their position on the WHO list. Recently, a test for diagnosing all clinical manifestations of Sporotrichosis according to antibody detection in patients' blood serum was developed, which may influence therapeutic decisions for treating this condition. Despite the significance of these accomplishments, some fungal diseases still require novel treatment and/or diagnostic techniques, indicating the requirement for innovation for fungal infections.
Along with government research funding to solve health issues, the academic research community should have access to increased investments in technologies focused on enhancing target validation and the safety of drugs. To facilitate the decision-making of regulatory bodies and investors, simplification of regulatory procedures is also relevant.
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