Two new reports have produced conflicting results on the potential effectiveness of remdesivir, an experimental antiviral drug considered to be one of the leading hopes in the fight against COVID-19. What you need to know:
In the study from China, 237 severely ill patients were randomly chosen to receive either remdesivir or abetween Feb. 6 and March 12 at 10 hospitals in Hubei, the province that includes Wuhan. Researchers had aimed to recruit 453 patients, but a steep decline in COVID-19 cases prevented them from reaching that goal.
The early results reported Wednesday by Gilead are based on an initial phase of the U.S.-led clinical trial involving 397 patients with severe COVID-19 assigned to receive either 5 or 10 days of remdesivir. There was no mention of a control or placebo group. More than 64% of the patients who received the shorter treatment course were discharged, compared with 54% of the group treated for 10 days.
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