Pregnancy outcomes after monoclonal antibodies infusion for COVID-19 MDPIOpenAccess UninaIT univUda Unibo antibody antibodies COVID19 coronavirus covid pregnancy
By Tarun Sai LomteFeb 8 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in Vaccines, researchers evaluated the impact of monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 on maternal-fetal health.
About the study The present study examined pregnancy outcomes after mAb treatment for COVID-19. A literature search in Web of Science, Cochrane library Embase, Medline, Scopus, and Ovid databases was performed using specific terms between December 1, 2019, and August 12, 2022. Search, eligibility, inclusion, risk of bias, and data extraction were performed by two authors.
Findings The researchers screened 53 articles and included 17 studies in the systematic review. Eight studies were conducted in the United States , four in Europe, three in Japan, and two in the United Arab Emirates . In total, these studies comprised 190 pregnant women with mild to severe COVID-19 who were treated with mAbs. mAbs were administered to 105 outpatients and 81 inpatients. One study did not specify out/in-patient status for four patients.
South Africa Latest News, South Africa Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Symptomatic SARS-CoV-2 infection during pregnancy increases risk of complications for mother and infantSymptomatic SARS-CoV-2 infection during pregnancy increases risk of complications for mother and infant SapienzaRoma SARSCoV2 COVID19 Pregancy Complications
Read more »
Mucoactive drugs block SARS-CoV-2 infectionMucoactive drugs block SARS-CoV-2 infection Coronavirus Disease COVID DrugDiscovery Mucoactive Mucociliary biorxivpreprint UofAlabama
Read more »
The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancyThe possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy IJMS_MDPI microbiome microbiota immune immunesystem pregnancy
Read more »
Researchers report two unusual COVID-19-related arrhythmic cases in childrenResearchers report two unusual COVID-19-related arrhythmic cases MDPIOpenAccess UniPadova covid coronavirus COVID19 arrhythmic
Read more »
Pandemic-related challenges faced by pregnant women, new mothers, and their families in maternal and newborn carePandemic-related challenges faced by pregnant women, new mothers, and their families in maternal and newborn care IJERPH_MDPI unibielefeld ChariteBerlin pregnancy women womenshealth maternalhealth newborn pandemic covid
Read more »
Tracking excess of maternal deaths associated with COVID-19 in Brazil: a nationwide analysis - BMC Pregnancy and ChildbirthBackground The COVID-19 pandemic brought a new challenge to maternal mortality in Brazil. Throughout 2020, Brazil registered 549 maternal deaths, mainly in second and third-trimester pregnant women. The objective of this study was to estimate the excess maternal deaths in Brazil caused directly and indirectly by Covid-19 in the year 2020. In addition, we sought to identify clinical, social and health care factors associated with the direct maternal deaths caused by Covid-19. Methods We performed nationwide analyses based on data from the Mortality Information System (SIM) for general and maternal deaths and the Influenza Epidemiological Surveillance System (SIVEP-Influenza) for estimates of female and maternal deaths due to COVID-19. Two distinct techniques were adopted. First, we describe maternal deaths directly caused by covid-19 and compare them with the historical series of deaths from covid-19 among women of childbearing age (15 to 49 years). Next, we estimated the total excess maternal mortality. Then, we calculated odds ratios for symptoms, comorbidities, social determination proxies and hospital care aspects between COVID-19 maternal deaths and deaths of women of childbearing age who were not pregnant or no maternal deaths. We chose women of childbearing age (15 to 49 years) as a reference because sex and age introduce differentials in the risk of COVID-19 death. Results Most maternal deaths occurred during pregnancy compared to postpartum deaths month by month in 2020 (μ = 59.8%, SD = 14.3%). The excess maternal mortality in 2020 in Brazil was 1.40 (95% CI 1.35–1.46). Even considering excess mortality due to COVID-19 for the childbearing age female population (MMR 1.14; 95% CI 1.13–1.15), maternal mortality exceeded the expected number. The odds of being a black woman, living in a rural area and being hospitalized outside the residence municipality among maternal deaths were 44, 61 and 28% higher than the control group. Odds of hospitalization (OR 4.37; 95
Read more »