An article published in BMCGeriatr discusses PRO-MADE: a prognostic model that can identify Alzheimer’s disease patients who are at high-risk of all-cause mortality within one-year of AD diagnosis to support timely referrals to palliative care.
]. The calibration slope was determined by regressing the observed mortality risks on predicted mortality risk probabilities. A slope of 1 would indicate the opposite []. Calibration-in-the-large is a basic measure to determine mean calibration and is estimated from the intercept of the regression curve. Negative values suggest an overestimation of predicted risks while positive values suggest an underestimation of the predicted risks.
Health status differed between both groups. When compared with survivors, the decedent group had a significantly higher proportion of patients with greater comorbidity burden, infections and abnormal biochemical values for haemoglobin, potassium, urea, and albumin. The proportion of patients reporting cognitive and mental health issues were similar in both groups, with the exception of a history of delirium being reportedly higher in the decedent group.
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