Perspective: Focusing on differences between the sexes is leading medical researchers astray
A bottle of Ambien. By Heather Shattuck-Heidorn and Sarah S. Richardson May 30 at 6:00 AM It’s a simple and critical fact of medical science that women’s bodies differ from men’s, and those differences can affect everything from diagnosis to treatment. For instance, women experiencing a heart attack often present different symptoms than men. Because doctors considered men’s symptoms the norm, they for years misdiagnosed heart conditions in women.
There’s nowhere that these challenges are clearer than with the sleep drug zolpidem, the basis of the popular sleep aid Ambien. In 2013, the Food and Drug Administration claimed that women should receive a lower dose of zolpidem than men because they clear the drug from their system more slowly and are more impaired by it at the 8-hour mark when people wake up and begin their day.
In short, there isn’t any scientific evidence supporting sex-based dosage for zolpidem. The drug clears quickly in both men and women and does not lead to greater impairment in women. [The Trump administration says it wants to define sex ‘on a biological basis.’ It gets the science wrong.]
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