Paving the Way for New Drugs through Particle Perfection 💊👇 Particle_Works SLAS_Org drugdiscovery lifesciences technology particles interview
Sponsored Content by Particle WorksMay 2 2023 insights from industryBen KnappettHead of Science and ApplicationsParticle Works Do particles hold the power to pave the way for new drugs? In this interview, we speak to Ben Knappett, Head of Science and Applications at Particle Works, to find out more!
We are trying to offer a suite of platforms with consistent pumping technology and microfluidic chips that can be used from the early stages of screening to manufacturing.From starting at Dolomite Microfluidics, you have over 20 years of experience working in particle technology. How has this evolved, and how does your expertise help meet your customers' needs? Dolomite Microfluidics was one of Blacktrace's earliest brands.
To most effectively deliver a therapeutic material into the body, it must be safely transported to the appropriate location, at the right time, to perform the correct function. At the same time, we need to avoid any immunogenic responses. It is important to avoid an overly aggressive immune response, which can be a negative symptomatic process for the patient. Once injected, getting the material to the right location is crucial to ensure that the therapeutic can be released effectively to do its job.
Our processes are highly complex, so it is also advantageous to see what others are offering, so we can find opportunities to integrate our platform into that process. The ANP System follows on from the ALiS platform. This system is used for the next step in the process, which is to determine the best process for efficiently manufacturing the formulation on a larger scale, while maintaining high encapsulation efficiency and particle size control, as well as low polydispersity.
Since the early 2010s, our microfluidics devices have been used to prepare lipid, polymer, hybrid and carbohydrate nanoparticles, as well as various other materials. We love working collaboratively, so engaging and figuring out how we might work with others in this space to provide better offerings to researchers is fantastic.
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