Long-term type 1 diabetes associated with accelerated brainaging jamanetworkopen
A, there was no significant difference observed between EDIC participants and controls without diabetes . In panel B, EDIC participants showed a significant increase in predicted brain age demonstrating more advanced brain aging patterns. SPARE-AD indicates spatial pattern for recognition-Alzheimer disease; SPARE-BA, spatial pattern for recognition-brain age.
Table 1. Association of Traditional Glycemic and Nonglycemic Risk Factors and Microvascular and Macrovascular Complications With MRI Outcomes Among 416 EDIC Participants, Adjusted for Age, Sex, and Scanner
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