Researchers have found that decay of tissues after death can be halted and cell functions restored based on early experiments in pigs that may eventually help increase the number of transplantable human organs.
Sixty minutes after stopping the heart in the anesthetized animals, Yale researchers were able to restart the circulation using a specialized machine and a synthetic fluid carrying oxygen and other components that promote cellular health and suppress inflammation.
Genetic analysis of the tissues suggested that molecular and cellular repair processes had begun once circulation had been restored, the researchers reported on Wednesday in the journal Nature. During the entire experiment, the pigs had no evidence of electrical activity in the brain, the researchers said.
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