Nature research paper: Omicron infection results in increased capacity of vaccinated people to neutralize Omicron and Delta, but a similar effect is not seen for unvaccinated people
, with or without previous vaccination, elicits protection against the previously dominant Delta variant is unclear. We measured SARS-CoV-2 variant neutralization capacity in 39 Omicron sub-lineage BA.1 infected individuals in South Africa starting at a median of 6 days post-symptoms onset and continuing until a last follow-up sample a median of 23 days post-symptoms to allow BA.1 elicited neutralizing immunity time to develop.
Khadija Khan, Farina Karim, Sandile Cele, Kajal Reedoy, Mallory Bernstein, Zesuliwe Jule, Yashica Ganga, Nokuthula Ngcobo, Matilda Mazibuko, Ntombifuthi Mthabela, Zoey Mhlane, Nikiwe Mbatha, Yoliswa Miya, Taryn Naidoo, Willem Hanekom, Kobus Herbst, Thandeka Khoza, Henrik Kløverpris, Alasdair Leslie, Mohlopheni Marakalala, Zaza Ndhlovu, Thumbi Ndung’u, Theresa Smit, Adrie Steyn, Emily Wong & Alex...
School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South AfricaKwaZulu-Natal Research Innovation and Sequencing Platform, Durban, South Africa James Emmanuel San, Houriiyah Tegally, Jennifer Giandhari, Yajna Ramphal, Richard J. Lessells & Tulio de OlveiraGila Lustig, Aida Sivro, Natasha Samsunder, Ayesha B. M. Kharsany, Quarraisha Abdool Karim, Salim S. Abdool Karim, Kogie Naidoo, Richard J. Lessells, Penny L. Moore, Tulio de Olveira & Alex Sigal
Centre for Epidemic Response and Innovation, School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South AfricaDepartment of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, IsraelDepartment of Medical Microbiology, University of KwaZulu-Natal, Durban, South AfricaNational Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South AfricaDepartment of Infectious Diseases, Nelson R.