The results were broadly consistent regardless of patients’ menopausal status or cancer progression status. Read more at straitstimes.com.
FRANKFURT - Novartis breast cancer drug Kisqali cut the risk of recurrence by more than 25 per cent in a pivotal trial on women diagnosed at an early stage, positioning the Swiss drugmaker to win new patients but facing strong competition from Eli Lilly.
The drug was used in the trial together with standard endocrine therapy to treat a type of cancer that grows in response to hormones and it was compared to endocrine therapy alone. Still, better drugs are needed after surgery because the cancer later returns in between a third and one half of cases. But Kisqali looks set to be a pioneer in a wider market because it was tested successfully in both high-risk and medium-risk patients, a population that is twice as large.
That compares with 8-20 per cent of the women in trials with Eli Lilly’s Verzenio being affected by severe diarrhoea.“We know diarrhoea can be a very troublesome, burdensome adverse event for patients taking anti-cancer medicines,” said Mr Jeff Legos, Head of Oncology & Hematology Development at Novartis.‘I worried if I would be normal again’: Breast cancer at 25 made new mother rethink life
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