Northwestern Medicine Performs Successful Double-Lung Transplant on Patients with Rare Condition

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Northwestern Medicine Performs Successful Double-Lung Transplant on Patients with Rare Condition
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Both Chicago-area patients have a rare genetic condition called situs inversus, where the organs in the chest and abdomen develop in a reversed or mirrored image from their normal positions.

CHICAGO --

The genetic condition, called situs inversus, affects about 1 in every 10,000 people, according to the Cleveland Clinic. Occurring during fetal development, the disorder has been linked to some 100 different genes. "Someone has tried to listen to their heart, and then they don't find the heartbeat on the left side, so they get an X-ray, and everything looks reversed," he said.

As her condition worsened, Vega said she could fill a 32-ounce cup or two with mucus she had coughed up each day. Just reattaching blood vessels created in utero for a left lung to openings on a "normal" right lung, for example, was especially difficult. In addition, Deer's and Vega's lungs were unique in how their backward organs had developed and grown new blood vessels to compensate for the reversal.

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