New protein–protein interactions designed by a computer

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New protein–protein interactions designed by a computer
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Research briefing: New protein–protein interactions designed by a computer

Creating protein interactions through computational design is a key challenge in the fields of both basic and translational biology.

An approach that uses the machine-learned fingerprints of protein-surface features was used to produce synthetic proteins that engage immunotherapeutic or viral targets with binding affinities comparable to those of naturally occurring proteins.

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Nature /  🏆 64. in US

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