Authors will be prompted to provide details on how sex and gender were considered in study design.
— will be raising awareness of the updated recommendations in letters to authors and reviewers during peer review. The aim here is to improve understanding of the degree to which sex and gender reporting is already part of study design, data collection and analysis in the research these journals publish. The journals will also evaluate author and reviewer reception of the changes so that we can iterate on them as we learn through experience.
The new measures are needed because research is still mostly failing to account for sex and gender in study design, sometimes with catastrophic results. Between 1997 and 2001, ten prescription drugs were withdrawn from use in the United States; eight of these were reported to have worse side effects in women than in men . These differences had probably been missed, in part, because of insufficient or inappropriate analysis of data on sex differences during clinical trials.
By introducing these changes, we aim to promote transparency in study design and, ultimately, make findings more accurate. Over time, we hope to see integration of sex and gender analysis in study design by default.
South Africa Latest News, South Africa Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Structural insights into the HBV receptor and bile acid transporter NTCP - NatureNature - Structural insights into the HBV receptor and bile acid transporter NTCP
Read more »
Turning Data Into Music May Help Scientists Study NatureWhat does COVID sound like? Some scientists are translating genetic code into musical notes to give melodies to all parts of life.
Read more »
Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2 - NatureNature - Characterization and antiviral susceptibility of SARS-CoV-2 Omicron/BA.2
Read more »
Inducible and reversible RNA N6-methyladenosine editing - Nature CommunicationsRNA modifications, including N6-methyladenosine (m6A), have been reported to regulate fundamental RNA processes and properties, and directly linked to various human diseases. Here, the authors develop a chemically inducible and reversible RNA m6A modification editing platform integrating chemically induced proximity (CIP) and CRISPR methods.
Read more »
Electrically driven reprogrammable phase-change metasurface reaching 80% efficiency - Nature CommunicationsThe authors demonstrate an efficient platform for electrically driven reconfigurable metasurfaces by using Ge2Sb2Te5 to realize non-volatile, reversible, multilevel, and fast optical modulation and wavefront engineering in the near-infrared spectral range.
Read more »
OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage - NatureNature research paper: OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage
Read more »