To diagnose MS, the central vein sign on brain MRI appears to work as well as oligoclonal bands in CSF, and combining the two biomarkers yields the highest predictive value for MS, a new study indicates. ECTRIMS2022
, the central vein sign on brain MRI appears to work as well as oligoclonal bands in cerebrospinal fluid , and combining the two biomarkers yields the highest predictive value for MS, a new study indicates.
CVS is an emerging neuroimaging biomarker for MS that may improve diagnostic accuracy and reduce the need for lumbar puncture. At initial presentation, sensitivity for MS diagnosis was 75% for OCBs, 83% for CVS"Select-3" , and 71% for CVS"Select-6" . He also said there is"active discussion as to whether central vein sign should be added to the diagnostic criteria for MS.
"However, this study doesn't fully support that argument just yet. It is retrospective with a tiny sample size, and the full way they standardized assessments and reporting haven't been fully reported," said Lakhan, who wasn't involved in the study.
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