It is the third time the building has been damaged in the past 12 months
Wellingborough MP Peter Bone's constituency office has been vandalised yet again. A brick was thrown through the office window earlier this month - the third time the building has been damaged in the past 12 months, he said.
"Whoever did that, if they think that I’m going to be intimidated by that, they’re wrong. Like members across the House, I came into this place to serve my country, to serve my constituents and stand up for what I think is right. “In the past, the people who have attacked the office or made malicious phone calls or made internet threats have all been caught,” he said, adding “whoever did this is likely to get caught. But that doesn’t really help the situation. I mean, what have we come to when people think that because a mainstream politician says whatever it is they don’t agree with, they think they can turn to violence?”
Speaking about threats and violence against MPs generally, Mr Bone said he was concerned about the role played by social media, adding that he got a lot of abuse online, and pointing out that incidents involving violence or threats were not specific to one political party.
South Africa Latest News, South Africa Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Frontiers | Prolyl-hydroxylase inhibitor-induced regeneration of alveolar bone and soft tissue in a mouse model of periodontitis through metabolic reprogrammingBone injuries and fractures reliably heal through a process of regeneration with restoration to original structure and function when the gap between adjacent sides of a fracture site is small. However, when there is significant volumetric loss of bone, bone regeneration usually does not occur. In the present studies, we explore a particular case of volumetric bone loss in a mouse model of human periodontal disease (PD) in which alveolar bone surrounding teeth is permanently lost and not replaced. This model employs the placement of a ligature around the upper second molar for 10 days leading to inflammation and bone breakdown and closely replicates the bacterially-induced inflammatory etiology of human PD to induce bone degeneration. After ligature removal, mice are treated with a timed-release formulation of a small molecule inhibitor of prolylhydroxylases (PHDi; 1,4-DPCA) previously shown to induce epimorphic regeneration of soft tissue in non-regenerating mice. This PHDi induces high expression of HIF-1α and is able to shift the metabolic state from OXPHOS to aerobic glycolysis, an energetic state used by stem cells and embryonic tissue. This regenerative response was completely blocked by siHIF1a. In these studies, we show that timed-release 1,4-DPCA rapidly and completely restores PD-affected bone and soft tissue with normal anatomic fidelity and with increased stem cell markers due to site-specific stem cell migration and/or de-differentiation of local tissue, periodontal ligament (PDL) cell proliferation, and increased vascularization. In-vitro studies using gingival tissue show that 1,4-DPCA indeed induces de-differentiation and the expression of stem cell markers but does not exclude the role of migrating stem cells. Evidence of metabolic reprogramming is seen by the expression of not only HIF-1a, its gene targets, and resultant de-differentiation markers, but also the metabolic genes Glut-1, Gapdh, Pdk1, Pgk1 and Ldh-a in the periodontal tissue.
Read more »
Aspirin as effective as blood thinner injections to prevent deadly complications in patients with bone fracturesPatients hospitalized with fractures typically receive an injectable blood thinner, low-molecular-weight heparin, to prevent life-threatening blood clots. A new clinical trial, however, found that inexpensive over-the-counter aspirin is just as effective. The findings, published today in the New England Journal of Medicine, may lead surgeons to change their practice and administer aspirin to these patients.
Read more »
Scots man saved by wife after choking on 'poker chip sized' bone in Aldi chickenJack Callard was looking forward to tucking into the katsu chicken tenders but says he has now been put off the product for life.
Read more »
Major UK airport closed by heavy snowfall as Brits face -2C bone chillerMANCHESTER Airport has closed both its runways after heavy snowfall. Yellow weather warnings for snow and ice are in force across the UK amid bone-chilling temperatures. The mercury plunged to a bi…
Read more »
Tickets for Rag 'n' Bone Man gig at Ludlow Castle go on general sale todayTickets for the Rag’n’Bone Man gig at Ludlow Castle in the summer went on sale at 10am after a postcode-limited pre-sale sold out in hours.
Read more »