This diabetes medication often results in weight loss, and doctors are looking into whether it can help people without the condition shed a few pounds as well.
, an obesity medicine physician and professor of medicine at Boston University School of Medicine. “We think inflammation begins the process of weight gain, and causes dysfunction in the neural pathways that lead to satiety in the brain,” she says. In other words, this inflammation may be preventing your brain from getting the “I’m full” signals that your hormones are trying to convey., you’re increasing the satiety hormones,” says Dr. Apovian.
In some cases, “metformin can still promote some weight loss,” says Malin. “There is evidence that metformin can induce weight loss of approximately 5-10 lbs. in people who have PCOS or psychiatric disorders” such as schizophrenia, he says. “A possible reason is that they have associated insulin resistance.”While some doctors will prescribe metformin for moderately overweight people without insulin issues, it is not clear from any research that it helps.
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