Little known adeno-associated viruses may be key to unexplained hepatitis in kids, studies say

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Little known adeno-associated viruses may be key to unexplained hepatitis in kids, studies say
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Scientists in the United Kingdom say they've found 'strong circumstantial evidence' linking an obscure type of sidekick virus called adeno-associated virus to unexplained cases of liver damage in children around the world.

Scientists in the United Kingdom say they've found "strong circumstantial evidence" linking an obscure type of sidekick virus called adeno-associated virus to unexplained cases of liver damage in children around the world.

In two new studies, scientists say they may have found a smoking gun in adeno-associated virus 2, which is different from advenovirus 41. "A remora is not like the best analogy, but it's sort of like that. It's got to have a host virus," said Alex Greninger, assistant director of the clinical virology laboratory at the University of Washington.

Beyond that, scientists say, not much is known about them. Researchers say this finding has them scratching their heads. Without exception, the researchers found high levels of adeno-associated virus 2 in the the liver tissue children who needed liver transplants because of unexplained, sudden hepatitis. But it was only present in the liver tissue from one child in the control group.

When adeno-associated viruses were present, herpes and adenoviruses -- which are needed for adeno-associated viruses to copy themselves -- were frequently found, too.

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