Emily is a health news writer based in London, United Kingdom. She holds a bachelor's degree in biology from Durham University and a master's degree in clinical and therapeutic neuroscience from Oxford University. She has worked in science communication, medical writing and as a local news reporter while undertaking journalism training.
For the first time, scientists have created detailed maps of immune cells in the placenta, showing how the cells defend the fetus from invaders during early pregnancy.
The scientists used the placentas to investigate how three major pathogens infect the organ: the parasites Plasmodium falciparum and Toxoplasma gondii, which cause malaria and toxoplasmosis, respectively; and Listeria monocytogenes, a bacterium responsible for an infection called listeriosis.
By submitting your information you agree to the Terms & Conditions and Privacy Policy and are aged 16 or over."While infections during pregnancy have been known to cause complications, including miscarriage and stillbirth, very little has been known about the underlying mechanisms," Regina Hoo, lead study author and a postdoctoral fellow at the Wellcome Sanger Institute in the U.K., said in a statement.
All three pathogens can also infect Hofbauer cells, the team found. For example, T. gondii can hide in them as a way to evade the immune system and travel around the fetus' body.
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