In a small study, people with type 2 diabetes maintained their weight loss on the low-carbohydrate ketogenic diet for a year after they stopped using Ozempic or similar medications
People with type 2 diabetes who stop using drugs like Ozempic or Wegovy that trigger weight loss can avoid regaining the lost pounds if they adopt a ketogenic diet. The finding, which comes from a small study, challenges the notion that people must take these medications indefinitely to prevent unwanted weight gain.belong to a class of medications called GLP-1 agonists, which reduce appetite and boost the release of insulin.
The researchers tracked weight and blood sugar levels in 308 adults living in the US with type 2 diabetes who received nutrition therapy at Virta Health. All of them were using GLP-1 agonists when they enrolled. Participants were advised to follow the ketogenic diet – meaning they were told to eat less than 30 grams of carbohydrates daily, or less than 50 grams if they were vegan, and about 1.5 grams of protein per kilogram of bodyweight.
Between three and nine months later, half of the participants discontinued using GLP-1 agonists. All participants continued to follow the ketogenic diet for an additional year. At this point, the researchers found no significant differences in weight or blood sugar levels between the two groups. On average, participants who stopped taking GLP-1 agonists only gained about a kilogram of weight. By comparison, those who continued taking the medications gained about 2 kilograms.
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