In a recent comprehensive review published in Cyborg Bionic Systems, researchers led by Keyi Li from the General Hospital of Northern Theater Command in Shenyang, along with international collaborators, detail significant advances in the identification and application of biomarkers for prostate cancer (PCa).
Beijing Institute of Technology Press Co., LtdAug 23 2024 In a recent comprehensive review published in Cyborg Bionic Systems, researchers led by Keyi Li from the General Hospital of Northern Theater Command in Shenyang, along with international collaborators, detail significant advances in the identification and application of biomarkers for prostate cancer .
One of the major highlights of the review is the discussion on gene fusions like TMPRSS2-ERG, which are prevalent in prostate cancer and serve as vital diagnostic indices. The presence of noncoding RNAs such as SNHG12 and proteins like PSA and PSMA also hold substantial promise in not only detecting the disease but also in understanding its progression and guiding therapy.
Moreover, the development of specific probes for biomarker detection is another area of rapid advancement. The review details innovations in creating fluorescent, electrochemical, and radionuclide probes that enhance the sensitivity and specificity of current diagnostic techniques.
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