STOCKHOLM — Hungarian scientist Katalin Kariko and United States colleague Drew Weissman, who met in line for a photocopier before making mRNA molecule discoveries together that paved the way for Covid-19 vaccines, won the 2023 Nobel Prize for Medicine on Monday (Oct 2).
Hungarian scientist Katalin Kariko and United States colleague Drew Weissman, who met in line for a photocopier before making mRNA molecule discoveries together that paved the way for Covid-19 vaccines, won the 2023 Nobel Prize for Medicine on Monday .
Dr Kariko was senior vice president and head of RNA protein replacement at BioNTech until 2022 and has since acted as an adviser to the company. She is also a professor at the University of Szeged in Hungary and adjunct professor at the University of Pennsylvania’s Perelman School of Medicine.
The Nobel winners showed in 2005 that adjustments to nucleosides, the molecular letters that write the mRNA’s genetic code, can keep the mRNA under the immune system’s radar."This year's Nobel Prize recognises their basic science discovery that fundamentally changed our understanding of how mRNA interacts with the immune system and had a major impact on society during the recent pandemic," said Dr Rickard Sandberg, member of the Nobel Assembly at Karolinska Institute.
The technology means a radical break from established biotech medicines, which are generated in complex reactors by genetically modified living cells, then isolated and purified.
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