Between 2010 and 2021, the proportion of drug overdose deaths in the US involving a combination of fentanyl and a stimulant such as cocaine or methamphetamine skyrocketed
or methamphetamine. That is a 50-fold increase from 2010 when less than 1 per cent of overdose deaths were attributed to the drug combination. They also found that by 2021, stimulants were the most common drugs involved in fentanyl-related overdose deaths in every US state. Previously, overdose deaths involving fentanyl usually occurred alongside prescription opioids,dominated by [concurrent] meth and fentanyl use,” says Shover.
Two factors probably underlie this change. First, people may be using stimulants to counteract the opioid’s sedative effect because sedation can leave them more vulnerable to robbery or assault, especially if they are experiencing homelessness, says
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