The panel meets Wednesday as some experts question whether getting additional doses every few months is a practical public health strategy.
The FDA may need to establish a new process to get those new shots approved quickly, he added."If you start combination vaccines, the question is, how much data do you need? How do you recruit the participants?"
Usually, the dominant strain of influenza circulating in any given flu season is a descendant from the last flu season. Gounder outlined several questions about the goals of future boosters. Will boosting, for example, raise antibody levels for more than three to four months? Will it broaden a person's immunity to protect against more variants? Will it provide greater protection against hospitalization and death, and how long will that last?
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